Down-Regulation of Protease-activated Receptor-1 Is Regulated by Sorting Nexin 1
Degradation or “down-regulation” of protease-activated receptor-1 (PAR1), a G protein-coupled receptor for thrombin, is critical for termination of receptor signaling. Toward understanding the molecular mechanisms by which activated PAR1 is internalized, sorted to lysosomes, and degraded, we investi...
Gespeichert in:
| Veröffentlicht in: | Mol Biol Cell |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Cell Biology
2002
|
| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117618/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12058063/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E01-11-0131 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|