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Pancreatic β-Cell Protein Granuphilin Binds Rab3 and Munc-18 and Controls Exocytosis

Granuphilin/Slp-4 is a member of the synaptotagmin-like protein family expressed in pancreatic β-cells and in the pituitary gland. We show by confocal microscopy that both granuphilin-a and -b colocalize with insulin-containing secretory granules positioned at the periphery of pancreatic β-cells. Ov...

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Detalhes bibliográficos
Main Authors: Coppola, Thierry, Frantz, Christian, Perret-Menoud, Véronique, Gattesco, Sonia, Hirling, Harald, Regazzi, Romano
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117613/
https://ncbi.nlm.nih.gov/pubmed/12058058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-02-0025
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