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Decreased intracellular calcium mediates the histamine H(3)-receptor-induced attenuation of norepinephrine exocytosis from cardiac sympathetic nerve endings

Activation of presynatic histamine H(3) receptors (H(3)R) down-regulates norepinephrine exocytosis from cardiac sympathetic nerve terminals, in both normal and ischemic conditions. Analogous to the effects of α(2)-adrenoceptors, which also act prejunctionally to inhibit norepinephrine release, H(3)R...

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Autori principali: Silver, Randi B., Poonwasi, Kumar S., Seyedi, Nahid, Wilson, Sandy J., Lovenberg, Timothy W., Levi, Roberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC117589/
https://ncbi.nlm.nih.gov/pubmed/11752397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012506099
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