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Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene
Apc is a gene associated with familial adenomatous polyposis coli (FAP) and its inactivation is a critical step in colorectal tumor formation. The protein product, adenomatous polyposis coli (APC), acts to down-regulate intracellular levels of β-catenin, a key signal transducer in the Wnt signaling....
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The National Academy of Sciences
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117555/ https://ncbi.nlm.nih.gov/pubmed/11756652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012264999 |
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