Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest

Neural crest-specific ablation of BMP type IA receptor (BMPRIA) causes embryonic lethality by embryonic day (E) 12.5, and this was previously postulated to arise from a myocardial defect related to signaling by a small population of cardiac neural crest cells (cNCC) in the epicardium. However, as BM...

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Autori principali: Nomura-Kitabayashi, Aya, Phoon, Colin K. L., Kishigami, Satoshi, Rosenthal, Julie, Yamauchi, Yasutaka, Abe, Kuniya, Yamamura, Ken-ichi, Samtani, Rajeev, Lo, Cecilia W., Mishina, Yuji
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781366/
https://ncbi.nlm.nih.gov/pubmed/19717734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00304.2009
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