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Quaternary structure of human fatty acid synthase by electron cryomicroscopy

We present the first three-dimensional reconstruction of human fatty acid synthase obtained by electron cryomicroscopy and single-particle image processing. The structure shows that the synthase is composed of two monomers, arranged in an antiparallel orientation, which is consistent with biochemica...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Brink, Jacob, Ludtke, Steven J., Yang, Chao-Yuh, Gu, Zei-Wei, Wakil, Salih J., Chiu, Wah
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117528/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.012589499
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