Neuropeptide B-deficient mice demonstrate hyperalgesia in response to inflammatory pain

Neuropeptide B (NPB) and neuropeptide W (NPW) have been recently identified as ligands for the G protein-coupled receptor (GPR) 7 and GPR8. The precise in vivo role of this neuropeptide-receptor pathway has not been fully demonstrated. In this paper, we report that NPB-deficient mice manifest a mild...

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Autors principals: Kelly, Michele A., Beuckmann, Carsten T., Williams, S. Clay, Sinton, Christopher M., Motoike, Toshiyuki, Richardson, James A., Hammer, Robert E., Garry, Mary G., Yanagisawa, Masashi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174999/
https://ncbi.nlm.nih.gov/pubmed/15983370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503795102
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