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Salt-sensitive hypertension in endothelin-B receptor–deficient rats

The role of the endothelin-B receptor (ET(B)) in vascular homeostasis is controversial because the receptor has both pressor and depressor effects in vivo. Spotting lethal (sl) rats carry a naturally occurring deletion in the ET(B) gene that completely abrogates functional receptor expression. Rats...

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Autori principali: Gariepy, Cheryl E., Ohuchi, Takashi, Williams, S. Clay, Richardson, James A., Yanagisawa, Masashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC377481/
https://ncbi.nlm.nih.gov/pubmed/10749572
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