Intra-articular injections of high-molecular-weight hyaluronic acid have biphasic effects on joint inflammation and destruction in rat antigen-induced arthritis

To assess the potential use of hyaluronic acid (HA) as adjuvant therapy in rheumatoid arthritis, the anti-inflammatory and chondroprotective effects of HA were analysed in experimental rat antigen-induced arthritis (AIA). Lewis rats with AIA were subjected to short-term (days 1 and 8, n = 10) or lon...

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Bibliografiske detaljer
Main Authors: Roth, Andreas, Mollenhauer, Jürgen, Wagner, Andreas, Fuhrmann, Reneè, Straub, Albrecht, Venbrocks, Rudolf A, Petrow, Peter, Bräuer, Rolf, Schubert, Harald, Ozegowski, Jörg, Peschel, Gundela, Müller, Peter J, Kinne, Raimund W
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174961/
https://ncbi.nlm.nih.gov/pubmed/15899053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1725
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