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Predominant activation of MAP kinases and pro‐destructive/pro‐inflammatory features by TNF α in early‐passage synovial fibroblasts via TNF receptor‐1: failure of p38 inhibition to suppress matrix metalloproteinase‐1 in rheumatoid arthritis
OBJECTIVE: To examine the relative importance of tumour necrosis factor‐receptor 1 (TNF‐R1) and TNF‐R2 and their signalling pathways for pro‐inflammatory and pro‐destructive features of early‐passage synovial fibroblasts (SFB) from rheumatoid arthritis (RA) and osteoarthritis (OA). METHODS: Cells we...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMJ Group
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1954705/ https://ncbi.nlm.nih.gov/pubmed/17223661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.062521 |
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