Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function
Efficient budding of HIV-1 from the plasma membrane of infected cells requires the function of a 6-kDa protein known as p6. A highly conserved Pro-Thr-Ala-Pro (PTAP) motif (the “late” or “L” domain), is critical for the virus-budding activity of p6. Recently, it was demonstrated that the product of...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805336/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.032511899 |
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