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Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function
Efficient budding of HIV-1 from the plasma membrane of infected cells requires the function of a 6-kDa protein known as p6. A highly conserved Pro-Thr-Ala-Pro (PTAP) motif (the “late” or “L” domain), is critical for the virus-budding activity of p6. Recently, it was demonstrated that the product of...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117412/ https://ncbi.nlm.nih.gov/pubmed/11805336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032511899 |
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