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Grafts of supplementary thymuses injected with allogeneic pancreatic islets protect nonobese diabetic mice against diabetes

In nonobese diabetic (NOD) mice, the autoimmune attack of the β-cells in pancreatic islets is now believed to result from abnormal thymic selection. Accordingly, grafts of thymic epithelium from NOD donors to athymic recipients promote autoimmune islet inflammation in normal strains, and intrathymic...

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Bibliografski detalji
Glavni autori: Salaün, J., Simmenauer, N., Belo, P., Coutinho, A., Le Douarin, N. M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC117398/
https://ncbi.nlm.nih.gov/pubmed/11792835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012597499
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