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Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors.

Nonobese diabetic (NOD) mice spontaneously develop a T-cell-mediated autoimmune disease that is similar in many respects to insulin-dependent diabetes mellitus in humans. T-cell clones that specifically recognize pancreatic islet cell antigens can be derived from NOD mice, and most of these have bee...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Candéias, S, Katz, J, Benoist, C, Mathis, D, Haskins, K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2068098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.14.6167
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