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Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors.

Nonobese diabetic (NOD) mice spontaneously develop a T-cell-mediated autoimmune disease that is similar in many respects to insulin-dependent diabetes mellitus in humans. T-cell clones that specifically recognize pancreatic islet cell antigens can be derived from NOD mice, and most of these have bee...

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Main Authors: Candéias, S, Katz, J, Benoist, C, Mathis, D, Haskins, K
格式: Artigo
語言:Inglês
出版: 1991
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC52043/
https://ncbi.nlm.nih.gov/pubmed/2068098
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