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Measurements of weak interactions between truncated substrates and a hammerhead ribozyme by competitive kinetic analyses: implications for the design of new and efficient ribozymes with high sequence specificity

Exploitation of ribozymes in a practical setting requires high catalytic activity and strong specificity. The hammerhead ribozyme R32 has considerable potential in this regard since it has very high catalytic activity. In this study, we have examined how R32 recognizes and cleaves a specific substra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kasai, Yasuhiro, Shizuku, Hideki, Takagi, Yasuomi, Warashina, Masaki, Taira, Kazunari
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC117203/
https://ncbi.nlm.nih.gov/pubmed/12034825
Etiketak: Etiketa erantsi
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