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Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily.

The Bacillus subtilis Sfp protein activates the peptidyl carrier protein (PCP) domains of surfactin synthetase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue conserved in all PCPs. Its wide PCP substrate spectrum renders Sfp a biotechnologically valuab...

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Detalhes bibliográficos
Main Authors: Reuter, K, Mofid, M R, Marahiel, M A, Ficner, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171745/
https://ncbi.nlm.nih.gov/pubmed/10581256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.23.6823
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