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Structure and function of an archaeal topoisomerase VI subunit with homology to the meiotic recombination factor Spo11.
In all organisms, type II DNA topoisomerases are essential for untangling chromosomal DNA. We have determined the structure of the DNA-binding core of the Methanococcus jannaschii DNA topoisomerase VI A subunit at 2.0 A resolution. The overall structure of this subunit is unique, demonstrating that...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171681/ https://ncbi.nlm.nih.gov/pubmed/10545127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.21.6177 |
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