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HDAC4 deacetylase associates with and represses the MEF2 transcription factor.
The acetylation state of histones can influence transcription. Acetylation, carried out by acetyltransferases such as CBP/p300 and P/CAF, is commonly associated with transcriptional stimulation, whereas deacetylation, mediated by the three known human deacetylases HDAC1, 2 and 3, causes transcriptio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171580/ https://ncbi.nlm.nih.gov/pubmed/10487761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.18.5099 |
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