A carregar...

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis.

To elucidate the biological role of Stat3 in the skin, conditional gene targeting using the Cre-loxP system was performed as germline Stat3 ablation leads to embryonic lethality. K5-Cre;Stat3(flox/-) transgenic mice, whose epidermal and follicular keratinocytes lack functional Stat3, were viable and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sano, S, Itami, S, Takeda, K, Tarutani, M, Yamaguchi, Y, Miura, H, Yoshikawa, K, Akira, S, Takeda, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171539/
https://ncbi.nlm.nih.gov/pubmed/10469645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.17.4657
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!