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DLX3-dependent STAT3 signaling in keratinocytes regulates skin immune homeostasis

Epidermal specific deletion of the homeobox transcription regulator DLX3 disrupts keratinocyte differentiation and results in an IL-17-linked psoriasis-like skin inflammation. To identify the epidermal initiating signals produced by DLX3-null keratinocytes, we performed acute deletion of DLX3 in adu...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Bhattacharya, Shreya, Kim, Jin-Chul, Ogawa, Youichi, Nakato, Gaku, Nagle, Veronica, Brooks, Stephen R., Udey, Mark C., Morasso, Maria I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988235/
https://ncbi.nlm.nih.gov/pubmed/29246798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.11.033
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