PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic.

Protein kinase C (PKC) has been implicated in integrin-mediated spreading and migration. In mammary epithelial cells there is a partial co-localization between beta1 integrin and PKCalpha. This reflects complexes between these proteins as demonstrated by fluorescense resonance energy transfer (FRET)...

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Autores principales: Ng, T, Shima, D, Squire, A, Bastiaens, P I, Gschmeissner, S, Humphries, M J, Parker, P J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171467/
https://ncbi.nlm.nih.gov/pubmed/10406796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.14.3909
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