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Ezrin is a downstream effector of trafficking PKC–integrin complexes involved in the control of cell motility

Protein kinase C (PKC) α has been implicated in β1 integrin-mediated cell migration. Stable expression of PKCα is shown here to enhance wound closure. This PKC-driven migratory response directly correlates with increased C-terminal threonine phosphorylation of ezrin/moesin/radixin (ERM) at the wound...

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Autors principals: Ng, Tony, Parsons, Maddy, Hughes, William E., Monypenny, James, Zicha, Daniel, Gautreau, Alexis, Arpin, Monique, Gschmeissner, Steve, Verveer, Peter J., Bastiaens, Philippe I.H., Parker, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125254/
https://ncbi.nlm.nih.gov/pubmed/11387207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2723
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