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Integrins control motile strategy through a Rho–cofilin pathway

During wound healing, angiogenesis, and tumor invasion, cells often change their expression profiles of fibronectin-binding integrins. Here, we show that β1 integrins promote random migration, whereas β3 integrins promote persistent migration in the same epithelial cell background. Adhesion to fibro...

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Detalhes bibliográficos
Main Authors: Danen, Erik H.J., van Rheenen, Jacco, Franken, Willeke, Huveneers, Stephan, Sonneveld, Petra, Jalink, Kees, Sonnenberg, Arnoud
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171933/
https://ncbi.nlm.nih.gov/pubmed/15866889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412081
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