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Dual Stimulation of Ras/Mitogen-Activated Protein Kinase and Rhoa by Cell Adhesion to Fibronectin Supports Growth Factor–Stimulated Cell Cycle Progression

In cellular transformation, activated forms of the small GTPases Ras and RhoA can cooperate to drive cells through the G1 phase of the cell cycle. Here, we show that a similar but substrate-regulated mechanism is involved in the anchorage-dependent proliferation of untransformed NIH-3T3 cells. Among...

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Bibliografische gegevens
Hoofdauteurs: Danen, Erik H.J., Sonneveld, Petra, Sonnenberg, Arnoud, Yamada, Kenneth M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150684/
https://ncbi.nlm.nih.gov/pubmed/11134071
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