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Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
The enzyme adenine phosphoribosyltransferase (APRT) functions to salvage adenine by converting it to adenosine-5-monophosphate (AMP). APRT deficiency in humans is a well characterized inborn error of metabolism, and APRT may contribute to the indispensable nutritional role of purine salvage in proto...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171432/ https://ncbi.nlm.nih.gov/pubmed/10393170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.13.3533 |
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