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Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization.
We searched for proteins that interact with Ras in interleukin (IL)-2-stimulated or IL-2-deprived cells, and found that the transcription factor Aiolos interacts with Ras. The Ras-Aiolos interaction was confirmed in vitro and in vivo by co-immunoprecipitation. Indirect immunofluorescence shows that...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171421/ https://ncbi.nlm.nih.gov/pubmed/10369681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.12.3419 |
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