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Bcl-2-regulated cell death signalling in the prevention of autoimmunity

Cell death mediated through the intrinsic, Bcl-2-regulated mitochondrial apoptosis signalling pathway is critical for lymphocyte development and the establishment of central and maintenance of peripheral tolerance. Defects in Bcl-2-regulated cell death signalling have been reported to cause or corre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tischner, D, Woess, C, Ottina, E, Villunger, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032315/
https://ncbi.nlm.nih.gov/pubmed/21364654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.27
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