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Inefficient processing impairs release of RNA from the site of transcription.
We describe here for the first time the site of retention within the nucleus of pre-mRNA processing mutants unable to be exported to the cytoplasm. Fluorescence in situ hybridization was used to detect transcripts from human beta-globin genes that are either normal or defective in splicing or 3'...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171366/ https://ncbi.nlm.nih.gov/pubmed/10329631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.10.2855 |
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