Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone.

Steroid receptor co-activator 1 (SRC-1) is a transcription co-factor that enhances the hormone-dependent action, mediated by the thyroid hormone (TH) receptor (TR) and other nuclear receptors. In vitro studies have shown that SRC-1 is necessary for the full expression of TH effect. SRC-1 knockout mi...

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Detalhes bibliográficos
Main Authors: Weiss, R E, Xu, J, Ning, G, Pohlenz, J, O'Malley, B W, Refetoff, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171275/
https://ncbi.nlm.nih.gov/pubmed/10202153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.7.1900
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