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Crystal structure of a heparin- and integrin-binding segment of human fibronectin.

The crystal structure of human fibronectin (FN) type III repeats 12-14 reveals the primary heparin-binding site, a clump of positively charged residues in FN13, and a putative minor site approximately 60 A away in FN14. The IDAPS motif implicated in integrin alpha4beta1 binding is at the FN13-14 jun...

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Bibliografske podrobnosti
Main Authors: Sharma, A, Askari, J A, Humphries, M J, Jones, E Y, Stuart, D I
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171236/
https://ncbi.nlm.nih.gov/pubmed/10075919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.6.1468
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