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Crystal structure of a heparin- and integrin-binding segment of human fibronectin.
The crystal structure of human fibronectin (FN) type III repeats 12-14 reveals the primary heparin-binding site, a clump of positively charged residues in FN13, and a putative minor site approximately 60 A away in FN14. The IDAPS motif implicated in integrin alpha4beta1 binding is at the FN13-14 jun...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171236/ https://ncbi.nlm.nih.gov/pubmed/10075919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.6.1468 |
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