Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo.

Phosphoinositide 3-kinases (PI3Ks) are lipid kinases which also possess an in vitro protein kinase activity towards themselves or their adaptor proteins. The physiological relevance of these phosphorylations is unclear at present. Here, the protein kinase activity of the tyrosine kinase-linked PI3K,...

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Autores principales: Vanhaesebroeck, B, Higashi, K, Raven, C, Welham, M, Anderson, S, Brennan, P, Ward, S G, Waterfield, M D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171219/
https://ncbi.nlm.nih.gov/pubmed/10064595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.5.1292
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