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A cytomegalovirus glycoprotein re-routes MHC class I complexes to lysosomes for degradation.

Mouse cytomegalovirus (MCMV) early gene expression interferes with the major histocompatibility complex class I (MHC class I) pathway of antigen presentation. Here we identify a 48 kDa type I transmembrane glycoprotein encoded by the MCMV early gene m06, which tightly binds to properly folded beta2-...

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Bibliografiske detaljer
Main Authors: Reusch, U, Muranyi, W, Lucin, P, Burgert, H G, Hengel, H, Koszinowski, U H
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171199/
https://ncbi.nlm.nih.gov/pubmed/10022849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.4.1081
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