Murine cytomegalovirus degrades MHC class II to colonize the salivary glands

Cytomegaloviruses (CMVs) persistently and systemically infect the myeloid cells of immunocompetent hosts. Persistence implies immune evasion, and CMVs evade CD8(+) T cells by inhibiting MHC class I-restricted antigen presentation. Myeloid cells can also interact with CD4(+) T cells via MHC class II...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Yunis, Joseph, Farrell, Helen E., Bruce, Kimberley, Lawler, Clara, Sidenius, Stine, Wyer, Orry, Davis-Poynter, Nicholas, Stevenson, Philip G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831752/
https://ncbi.nlm.nih.gov/pubmed/29447285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006905
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi