Murine cytomegalovirus degrades MHC class II to colonize the salivary glands

Cytomegaloviruses (CMVs) persistently and systemically infect the myeloid cells of immunocompetent hosts. Persistence implies immune evasion, and CMVs evade CD8(+) T cells by inhibiting MHC class I-restricted antigen presentation. Myeloid cells can also interact with CD4(+) T cells via MHC class II...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Yunis, Joseph, Farrell, Helen E., Bruce, Kimberley, Lawler, Clara, Sidenius, Stine, Wyer, Orry, Davis-Poynter, Nicholas, Stevenson, Philip G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831752/
https://ncbi.nlm.nih.gov/pubmed/29447285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006905
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