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A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface.

Murine cytomegalovirus (MCMV) interferes with antigen presentation by means of retaining major histocompatibility complex (MHC) class I molecules in the endoplasmic reticulum (ER). Here we identify and characterize an MCMV-encoded glycoprotein, gp34, which tightly associates with properly conformed...

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Detalles Bibliográficos
Main Authors: Kleijnen, M F, Huppa, J B, Lucin, P, Mukherjee, S, Farrell, H, Campbell, A E, Koszinowski, U H, Hill, A B, Ploegh, H L
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169670/
https://ncbi.nlm.nih.gov/pubmed/9049298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.4.685
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