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A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface.

Murine cytomegalovirus (MCMV) interferes with antigen presentation by means of retaining major histocompatibility complex (MHC) class I molecules in the endoplasmic reticulum (ER). Here we identify and characterize an MCMV-encoded glycoprotein, gp34, which tightly associates with properly conformed...

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Detalhes bibliográficos
Main Authors: Kleijnen, M F, Huppa, J B, Lucin, P, Mukherjee, S, Farrell, H, Campbell, A E, Koszinowski, U H, Hill, A B, Ploegh, H L
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169670/
https://ncbi.nlm.nih.gov/pubmed/9049298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.4.685
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