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Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome.

The kinetic mechanism of elongation factor Tu (EF-Tu)-dependent binding of Phe-tRNAPhe to the A site of poly(U)-programmed Escherichia coli ribosomes has been established by pre-steady-state kinetic experiments. Six steps were distinguished kinetically, and their elemental rate constants were determ...

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Main Authors: Pape, T, Wintermeyer, W, Rodnina, M V
格式: Artigo
語言:Inglês
出版: 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171092/
https://ncbi.nlm.nih.gov/pubmed/9857203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.24.7490
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