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Inhibition by Elongation Factor EF G of Aminoacyl-tRNA Binding to Ribosomes

Elongation factor G (EF G), bound to ribosomes either with GMPPCP or with fusidic acid and GDP, inhibits elongation factor Tu (EF Tu)-dependent binding of Phe-tRNA on the ribosome-poly(U) complex and binding of Ala-tRNA on the initiation complex formed with RNA from bacteriophage R17; GTP hydrolysis...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Cabrer, Bartolomé, Vázquez, David, Modolell, Juan
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1972
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4551985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.3.733
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