Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo.

Ítems similars

• A single point mutation in erbA restores the erythroid transforming potential of a mutant avian erythroblastosis virus (AEV) defective in both erbA and erbB oncogenes.
  per: Damm, K, et al.
  Publicat: (1987)
• Recruitment of the Oncoprotein v-ErbA to Aggresomes
  per: Bondzi, Cornelius, et al.
  Publicat: (2010)
• Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR.
  per: Barettino, D, et al.
  Publicat: (1993)
• Targeting of N-CoR and histone deacetylase 3 by the oncoprotein v-ErbA yields a chromatin infrastructure-dependent transcriptional repression pathway
  per: Urnov, Fyodor D., et al.
  Publicat: (2000)
• Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype.
  per: Fuerstenberg, S, et al.
  Publicat: (1992)