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Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP-65 and Syk.

The binding of antigen to the B cell antigen receptor (BCR) results in the activation of protein tyrosine kinases (PTKs) such as Lyn and Syk, and the phosphorylation of several substrate proteins including HS1 and SLP-65. How these signaling elements are connected to the BCR is not well understood....

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Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Y, Wienands, J, Zürn, C, Reth, M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1998
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171076/
https://ncbi.nlm.nih.gov/pubmed/9857187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.24.7304
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