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Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP-65 and Syk.
The binding of antigen to the B cell antigen receptor (BCR) results in the activation of protein tyrosine kinases (PTKs) such as Lyn and Syk, and the phosphorylation of several substrate proteins including HS1 and SLP-65. How these signaling elements are connected to the BCR is not well understood....
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1998
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171076/ https://ncbi.nlm.nih.gov/pubmed/9857187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.24.7304 |
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