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Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk.

At the onset of S phase, chromosomal replication is initiated by the loading of DNA polymerase alpha onto replication origins. However, the molecular mechanisms for controlling the initiation are poorly understood. Using Xenopus egg extract, we report here the identification of a Xenopus homolog of...

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Autori principali: Mimura, S, Takisawa, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170898/
https://ncbi.nlm.nih.gov/pubmed/9755170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.19.5699
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