Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection.

After rearrangement of the T-cell receptor (TCR) beta-locus, early CD4(-)/CD8(-) double negative (DN) thymic T-cells undergo a process termed 'beta-selection' that allows the preferential expansion of cells with a functional TCR beta-chain. This process leads to the formation of a rapidly...

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Bibliografiske detaljer
Main Authors: Schmidt, T, Karsunky, H, Rödel, B, Zevnik, B, Elsässer, H P, Möröy, T
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170861/
https://ncbi.nlm.nih.gov/pubmed/9736613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.18.5349
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