Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria.

We have exploited the recently developed ability to trans- fect the malaria parasite Plasmodium falciparum to investigate the role of polymorphisms in the enzyme dihydropteroate synthase (DHPS), identified in sulfadoxine-resistant field isolates. By using a truncated form of the dhps gene, specific...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Triglia, T, Wang, P, Sims, P F, Hyde, J E, Cowman, A F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170716/
https://ncbi.nlm.nih.gov/pubmed/9669998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.14.3807
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi