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Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation.

Bruton's tyrosine kinase (Btk) is essential for B-lineage development and represents an emerging family of non-receptor tyrosine kinases implicated in signal transduction events initiated by a range of cell surface receptors. Increased dosage of Btk in normal B cells resulted in a striking enha...

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Detalhes bibliográficos
Main Authors: Fluckiger, A C, Li, Z, Kato, R M, Wahl, M I, Ochs, H D, Longnecker, R, Kinet, J P, Witte, O N, Scharenberg, A M, Rawlings, D J
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170543/
https://ncbi.nlm.nih.gov/pubmed/9524120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.7.1973
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