The mitochondrial DNA polymerase as a target of oxidative damage
The mitochondrial respiratory chain is a source of reactive oxygen species (ROS) that are responsible for oxidative modification of biomolecules, including proteins. Due to its association with mitochondrial DNA, DNA polymerase γ (pol γ) is in an environment to be oxidized by hydrogen peroxide and h...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2002
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12087165/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf392 |
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