The mitochondrial DNA polymerase as a target of oxidative damage

The mitochondrial respiratory chain is a source of reactive oxygen species (ROS) that are responsible for oxidative modification of biomolecules, including proteins. Due to its association with mitochondrial DNA, DNA polymerase γ (pol γ) is in an environment to be oxidized by hydrogen peroxide and h...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Graziewicz, Maria A., Day, Brian J., Copeland, William C.
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 2002
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12087165/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf392
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