The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1.

Biosynthesis of glycosylphosphatidylinositol (GPI) is initiated by transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This chemically simple step is genetically complex because three genes are required in both mammals and yeast. Mammalian PIG-A and PIG-C are homol...

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Detalhes bibliográficos
Main Authors: Watanabe, R, Inoue, N, Westfall, B, Taron, C H, Orlean, P, Takeda, J, Kinoshita, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170437/
https://ncbi.nlm.nih.gov/pubmed/9463366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.4.877
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