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Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27.
The p27(Kip1) protein associates with G1-specific cyclin-CDK complexes and inhibits their catalytic activity. p27(Kip1) is regulated at various levels, including translation, degradation by the ubiquitin/proteasome pathway and non-covalent sequestration. Here, we describe point mutants of p27 defici...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
1997
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170165/ https://ncbi.nlm.nih.gov/pubmed/9311993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.17.5334 |
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