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Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27.

The p27(Kip1) protein associates with G1-specific cyclin-CDK complexes and inhibits their catalytic activity. p27(Kip1) is regulated at various levels, including translation, degradation by the ubiquitin/proteasome pathway and non-covalent sequestration. Here, we describe point mutants of p27 defici...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Vlach, J, Hennecke, S, Amati, B
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1997
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170165/
https://ncbi.nlm.nih.gov/pubmed/9311993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.17.5334
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